Atmospheric pressure plasma treated PLGA for tissue engineering

Summary form only given. Atmospheric pressure plasmas are attractive for many industrial applications such as improvement of adhesion, surface modification, sterilization, etc. Atmospheric pressure plasma is conducted for tissue engineering. PLGA (poly(latic-co-glycolic)acid), a biodegradable polymer, is selected as a scaffold. A series of gases were used for plasma treatment of PLGA under various conditions such as atmosphere, electric power, and time. Plasma characteristics are investigated by oscilloscope and OES (optical emission spectroscopy). Surface properties are also investigated, which are surface hydrophilicity, surface energy with high polar component, O-containing groups, and N-containing groups. From these results, we can expect that atmospheric pressure plasma treatment will be an effective process for culturing cells on PLGA.