CMOS front-end architecture for In-Vivo biomedical implantable devices

An integrated front-end architecture for in-vivo detection is presented. The system is conceived to be implanted under the human skin. The powering and communication between this device and an external primary transmitter are based on an inductive link. The presented architecture is oriented to two different approaches, defining a true/false alarm system, based on amperometric or impedance biosensors. The particular case of the amperometric sensor is used to validate the architecture in terms of different integrated modules fabricated in a 0.13 ¿m technology. A potentiostat amplifier has been integrated to control an amperometric biosensor as well as a current sensing method based on a transimpedance amplifier is used to measure the current. It is also introduced the electronics designed for the bio-impedance case.