DocumentCode :
3504524
Title :
Surface-based method to evaluate global brain shape asymmetries in human and chimpanzee brains
Author :
Fournier, Marc ; Combès, Benoît ; Roberts, Neil ; Keller, Simon ; Crow, Tim J. ; Hopkins, William D. ; Prima, Sylvain
Author_Institution :
INSERM, IRISA-INRIA VisAGeS Project-Team, Rennes, France
fYear :
2011
fDate :
March 30 2011-April 2 2011
Firstpage :
310
Lastpage :
316
Abstract :
In this paper we use humans and chimpanzees brain MRI databases to develop methods for evaluating global brain asymmetries. We perform brain segmentation and hemispheric surface extraction on both populations. The human brain segmentation pipeline is adapted to chimpanzees in order to obtain results of good quality. To alleviate the problems due to cortical variability we propose a mesh processing algorithm to compute the brain global shape. Surface-based global brain asymmetries are computed on chimpanzee and human subjects using individual mid-sagittal plane evaluation and population-level mean shape estimation. Asymmetry results are presented in terms of axis-wise components in order to perform more specific evaluation and comparison between the two populations.
Keywords :
biomedical MRI; brain; feature extraction; image segmentation; medical image processing; mesh generation; neurophysiology; pipeline arithmetic; MRI databases; axis-wise components; brain global shape; brain segmentation pipeline; chimpanzee brains; cortical variability; global brain shape asymmetries; hemispheric surface extraction; mesh processing algorithm; mid-sagittal plane evaluation; population-level mean shape estimation; surface-based method; Brain; Color; Estimation; Humans; Shape; Surface treatment; Torque; Axis-wise asymmetry components; Brain global shape computation; Chimp and human asymmetries comparison; Chimps MRI brain segmentation; Surfaced-based bilateral brain asymmetries;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on
Conference_Location :
Chicago, IL
ISSN :
1945-7928
Print_ISBN :
978-1-4244-4127-3
Electronic_ISBN :
1945-7928
Type :
conf
DOI :
10.1109/ISBI.2011.5872412
Filename :
5872412
Link To Document :
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