Title :
Fast virtual destaining of immunocytological specimens
Author :
Bell, A.A. ; Friedrich, D. ; Chaisaowong, K. ; Braunschweig, T. ; Knüchel-Clarke, R. ; Aach, T.
Author_Institution :
Inst. of Imaging & Comput. Vision, RWTH Aachen Univ., Aachen, Germany
fDate :
March 30 2011-April 2 2011
Abstract :
Microscopy-based diagnosis of certain diseases or infections, e.g. with human papilloma viruses (HPV) for the identification of high risk patients for cervical cancer, relies more and more often on immunocytochemical marker stains. These markers stain cells that exhibit a particular protein. In addition to one or more marker stains, pathologists need to simultaneously assess the morphology of the cell. Therefore the specimens are commonly also stained with a counter stain.
Keywords :
biochemistry; biomedical optical imaging; cancer; cellular biophysics; image colour analysis; medical image processing; molecular biophysics; optical microscopy; proteins; cell morphology; cervical cancer; color space conversion; diseases; fast virtual destaining; human papilloma viruses; immunocytochemical marker stains; immunocytological specimens; infections; microscopy-based diagnosis; protein; specific color transformation; Image color analysis; Microscopy; Optical attenuators; Optical imaging; Optical sensors; Radiation detectors; Table lookup; cancer diagnosis; color separation; cytology; immunocytochemical marker; virtual destaining;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on
Conference_Location :
Chicago, IL
Print_ISBN :
978-1-4244-4127-3
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2011.5872552
