Title :
Developmental evolution of dendritic morphology in a multi-compartmental neuron model
Author :
Rust, Alistair G. ; Adams, Rod
Author_Institution :
Dept. of Comput. Sci., Hertfordshire Univ., Hatfield, UK
Abstract :
Through the use of a multi-compartmental neuron simulation, Mainen and Sejnowski (1996) demonstrated that spike generation in neurons is a function of their dendritic structure. We investigate the determination of dendritic morphology given a desired set of spike traces. A genetic algorithm is used to identify optimal parameters for a developmental model which simulates the growth of 3-dimensional dendrites. For two classes of neurons with different spiking behaviour, the developmental evolutionary process discovers ranges of viable dendritic morphologies which satisfactorily match the desired spike traces
Keywords :
neurophysiology; dendritic morphology; dendritic structure; developmental evolution; multi-compartmental neuron model; multi-compartmental neuron simulation; spike generation; spike traces;
Conference_Titel :
Artificial Neural Networks, 1999. ICANN 99. Ninth International Conference on (Conf. Publ. No. 470)
Conference_Location :
Edinburgh
Print_ISBN :
0-85296-721-7
DOI :
10.1049/cp:19991139
