Construction of a 4D atlas of the developing brain using non-rigid registration

Author

Serag, Ahmed ; Aljabar, Paul ; Counsell, Serena ; Boardman, James ; Hajnal, Joseph V. ; Rueckert, Daniel

Author_Institution

Dept. of Comput., Imperial Coll. London, London, UK

fYear

2011

fDate

March 30 2011-April 2 2011

Firstpage

1532

Lastpage

1535

Abstract

In this paper we present an approach for constructing a 4D brain atlas of MR images of preterm baby infants aged between 26-44 weeks of gestation at time of scan. The method used for the creation of an average 4D atlas is based on the use of pair-wise non-rigid registration to eliminate bias in the atlas towards any of the original images. In addition, we use kernel regression to produce age-dependent anatomical templates. The resulting unbiased 4D atlas is much sharper than currently available atlases created using affine registration.

Keywords

biomedical MRI; brain; image registration; medical image processing; paediatrics; regression analysis; 4D atlas construction; MR images; affine registration; age-dependent anatomical templates; developing brain; gestation; kernel regression; nonrigid registration; preterm baby infants; time 26 week to 44 week; Biomedical imaging; Brain; Kernel; Pediatrics; Probabilistic logic; Shape; 4D atlas; MRI; brain development; neonatal; spatio-temporal;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging: From Nano to Macro, 2011 IEEE International Symposium on

Conference_Location

Chicago, IL

ISSN

1945-7928

Print_ISBN

978-1-4244-4127-3

Electronic_ISBN

1945-7928

Type

conf

DOI

10.1109/ISBI.2011.5872693

Filename

5872693