Title :
Challenges in modelling biofluids in microchannels
Author :
Xue, Xiangdong ; Patel, Mayur K. ; Bailey, Chris ; Kersaudy-Kerhoas, Maïwenn ; Desmulliez, Marc P Y
Author_Institution :
Sch. of Comput. & Math. Sci., Univ. of Greenwich, London
Abstract :
This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction in microscope. A T-microchannel design is numerically analysed by means of computational fluid dynamics (CFD) to investigate the effectiveness of blood separation based on the bifurcation law and other bio-physical effects. The simulation shows that the device can separate blood cells from plasma.
Keywords :
bifurcation; bioMEMS; blood; cellular biophysics; computational fluid dynamics; microfluidics; T-microchannel device; bifurcation law; bio-physical effects; biofluids; blood cells; blood separation; computational fluid dynamics; microfluids; particle interaction; shear rate performance; viscous forces; Bifurcation; Biological system modeling; Blood; Cells (biology); Computational fluid dynamics; Computational modeling; Microchannel; Microfluidics; Plasma devices; Plasma simulation;
Conference_Titel :
Electronics System-Integration Technology Conference, 2008. ESTC 2008. 2nd
Conference_Location :
Greenwich
Print_ISBN :
978-1-4244-2813-7
Electronic_ISBN :
978-1-4244-2814-4
DOI :
10.1109/ESTC.2008.4684363
