Title :
The effects of extremely low frequency pulsed electromagnetic fields (ELF) on human lymphocyte proliferation in vitro and DNA repair
Author :
Bersani, F. ; Franceschi, C. ; Monti, D. ; Bologni, A. ; Gatti, C. ; Cadossi, R. ; Nichelatti, M. ; Moschini, G. ; Cossarizza, A.
Author_Institution :
Dept. of Phys., Bologna Univ., Italy
Abstract :
The effect of extremely-low-frequency electromagnetic fields on in-vitro mitogen-induced lymphocyte proliferation was studied in two groups of healthy subjects (23 and 85 years, mean ages). An increase of cell proliferation was observed to be much higher in the group of aged subjects. The effects depended on the mitogen dose and involved interleukin-2 production and/or utilization. The DNA repair capability and cell survival in the exposed cultures after gamma irradiation was also evaluated, and no genotoxic effect was found.<>
Keywords :
DNA; biological effects of fields; biological effects of gamma-rays; biomolecular effects of radiation; blood; cellular effects of radiation; 23 to 85 yr; DNA repair; ELF; aged subjects; cell survival; exposed cultures; gamma irradiation; healthy subjects; human lymphocyte proliferation; in-vitro mitogen-induced lymphocyte proliferation; interleukin-2 production; low frequency pulsed electromagnetic fields;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.95245
