Title :
Design and performance of an endoscopic OCT system for in vivo studies of human mucosa
Author :
Feldchtein, F.I. ; Gelikonov, V.M. ; Gelikonov, G.V. ; Kuranov, R.V. ; Gladkova, N.D. ; Sergeev, A.M. ; Shakhova, N.M. ; Kuznetzova, I.A. ; Denisenko, A.N. ; Streltzova, O.S.
Author_Institution :
Inst. of Appl. Phys., Acad. of Sci., Nizhny Novgorod, Russia
Abstract :
Summary form only given. A key problem for endoscopic application of optical coherence tomography (OCT) is to provide a reliable and convenient access of probing low-coherence radiation to the surface of internal organs. Here, the authors describe the design and performance of their OCT systems integrated in standard endoscopes, operating in parallel with them and thus enhancing essentially the capabilities of endoscopy as a whole. Implementation of an extended flexible arm of the OCT interferometer to provide access to the studied tissue is based on the usage of polarization maintaining fibers for transportation of the low coherence light. The sampling arm of the fiber interferometer is terminated by a newly developed miniaturized electro-mechanical unit that controls the lateral scanning process. The probe beam swinging on the tissue surface approaches 2 mm. As a source of radiation the authors employ a superluminescent diode with a central frequency of 830 nm, bandwidth of 30 nm, and power of 1.5 mW. In-depth scanning is performed with an integrated piezo-optical modulator that introduces the difference in the length arms of the interferometer. With a scanning rate of 30 cm/s and an image depth of 3 mm, an OCT picture is acquired in approximately 1 s. This rate is sufficient to eliminate the effect of internal organ movement on the image quality. The electro-mechanical scanner has a size that fits the diameter and the curvature radius of an endoscope biopsy channel.
Keywords :
biomedical equipment; biomedical imaging; light coherence; light interferometers; optical tomography; superluminescent diodes; 1 s; 1.5 mW; 3 mm; 830 nm; endoscope biopsy channel; endoscopic OCT system; fiber interferometer; human mucosa; image quality; in vivo studies; integrated piezo-optical modulator; internal organ movement; lateral scanning process; low coherence light; low-coherence radiation; medical diagnostic imaging; medical instrumentation; miniaturized electro-mechanical unit; optical coherence tomography; polarization maintaining fibers; probe beam; superluminescent diode radiation source; tissue surface; Biomedical optical imaging; Endoscopes; In vivo; Optical fiber polarization; Optical interferometry; Probes; Sampling methods; Termination of employment; Tomography; Transportation;
Conference_Titel :
Lasers and Electro-Optics, 1998. CLEO 98. Technical Digest. Summaries of papers presented at the Conference on
Conference_Location :
San Francisco, CA, USA
Print_ISBN :
1-55752-339-0
DOI :
10.1109/CLEO.1998.675950