DocumentCode :
3520725
Title :
Photometric method of estimation of coagulation process parameters
Author :
Nosova, Ekaterina V. ; Aristov, Alexander A. ; Nefedova, Natalia S.
Author_Institution :
Tomsk Polytech. Univ., Tomsk, Russia
fYear :
2015
fDate :
June 29 2015-July 3 2015
Firstpage :
586
Lastpage :
590
Abstract :
Article is devoted to the development of a new method of carrying out coagulation tests based on photometric study of bioliquid droplet samples. The initial methodology of carrying out experiments and the analysis of a shape of obtained photometric curves are given. It is defined that the most informative are the optical curves obtained at the receiver location in the optical focus of droplet test, formed after the coagulation process. Researches on improvement of the methodology of carrying out experiments in order to increase the sensitivity and repeatability of our method are presented. A methodology of reagent´s introduction to photometric cuvette was determined. A comparative analysis of the behavior of the photometric curves, depending on the method of reagent´s mixing is carried out. In process of determine the optimal characteristics of the optical system, it is found that the highest sensitivity is achieved by using small angular apertures of the receiving device.
Keywords :
bio-optics; biological specimen preparation; biomedical measurement; blood; coagulation; drops; mixing; photometry; bioliquid droplet sample; coagulation parameter estimation; coagulation test; comparative analysis; droplet test; optical curve; optical focus; optimal optical system characteristics; photometric curve shape analysis; photometric cuvette; photometric method; reagent introduction; reagent mixing dependence; receiving device small angular aperture; repeatability; sensitivity; Apertures; Coagulation; Optical mixing; Optical receivers; Optical sensors; Optical variables control; Plasmas; coagulation; drop; fibrin clot; plasma; tehplastin;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Micro/Nanotechnologies and Electron Devices (EDM), 2015 16th International Conference of Young Specialists on
Conference_Location :
Erlagol
ISSN :
2325-4173
Print_ISBN :
978-1-4673-6718-9
Type :
conf
DOI :
10.1109/EDM.2015.7184611
Filename :
7184611
Link To Document :
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