Abstract :
Interstitial hyperthermia using magnetic materials is an excellent method in selectively heating cancer tissue without damaging the normal one. In this method, a ferromagnetic material is implanted in the cancer tissue and heated under a high frequency alternating magnetic field. The temperature of the cancer is raised and then regulated at Curie temperature(Tc) of the implant material. Therefore, the implant material should possess large heat generation ability and the suitable Tc and should be composed by bio-compatible elements such as C, O, N, Na, Mg, Si, K, Ca, Ti, Fe. In this study, the magnetic properties and characteristic of heat generation for the nano-particle of MgFe2O4 are reported. The nano-particle were prepared from MgCl2 (0.98%) and FeCl3 (95%) using coprecipitation. The precipitate was annealed at 773-1273 K for 6 hours. The particle size was dependent on the annealing temperature. The study showed that the quantity of heat generation increases with increasing particle size. The nanoparticles with 160 nm of MgFe2O4 have a heat generation value of 18W/g, which is equal to Fe0.73Pt0.27 bulk implant.
Keywords :
Curie temperature; annealing; biomagnetism; cancer; ferromagnetic materials; hyperthermia; magnesium compounds; nanoparticles; nanotechnology; particle size; precipitation; prosthetics; radiation therapy; tumours; 160 nm; 6 hour; 773 to 1273 K; Curie temperature; MgFe2O4; annealing; biocompatible elements; bulk implant; cancer tissue heating; cancer treatment; coprecipitation; ferromagnetic material; heat generation; high frequency alternating magnetic field; implant material; interstitial hyperthermia; magnetic properties; nanoparticle; particle size; Annealing; Biological materials; Cancer; Character generation; Frequency; Heating; Hyperthermia; Implants; Iron; Magnetic materials;
