DocumentCode
3530630
Title
On the Effectiveness of Distances Measuring Protein Structure Similarity
Author
Galgonek, Jakub ; Hokzsa, David
Author_Institution
Dept. of Software Eng., Charles Univ. in Prague, Prague, Czech Republic
fYear
2009
fDate
29-30 Aug. 2009
Firstpage
165
Lastpage
166
Abstract
Determining similarity between two protein structures is one of the most fundamental problems in contemporary structural bioinformatics. With the increasing complexity of the measures, their effectiveness increases as well. However, other important observables, such as the degree of metric properties fulfilment, could rather deteriorate than improve. In this paper we introduce an effective measure and study its degree of metric properties fulfilment.
Keywords
bioinformatics; molecular biophysics; proteins; contemporary structural bioinformatics; measurement complexity; metric properties; protein structure similarity; Amino acids; Application software; Bioinformatics; Databases; Heuristic algorithms; Mathematics; Physics; Protein engineering; Software engineering; Software measurement; Protein Structure; SCOP; TM-score;
fLanguage
English
Publisher
ieee
Conference_Titel
Similarity Search and Applications, 2009. SISAP '09. Second International Workshop on
Conference_Location
Prague
Print_ISBN
978-0-7695-3765-8
Type
conf
DOI
10.1109/SISAP.2009.19
Filename
5271931
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