DocumentCode :
3533108
Title :
A text-mining approach for classification of genomic fragments
Author :
Gadia, Vinay ; Rosen, Gail
Author_Institution :
Dept. of Electr. & Comput. Eng., Drexel Univ., Philadelphia, PA
fYear :
2008
fDate :
3-5 Nov. 2008
Firstpage :
107
Lastpage :
108
Abstract :
Genome identification is an emerging area of interest due to the study of environmental DNA samples. We show that performance approaches 50% for classifying 500 bp fragments when using 12 mer features, but more importantly, the performance linearly increases for large N. Secondly, we determine that an inverted TF-IDF measure performs 16% better when only using 80% of the words, as opposed to taking the fullset (100%). This increase implies that while too sparse of a feature subset does not produce good results, a carefully selected set has the potential to improve genome classification over a random feature set. Computing even 80% of all possible features can result in a significant savings in computation. The Euclidean classifier and TF-IDF measures will pave the way for more discriminative classification techniques.
Keywords :
biocomputing; biology computing; data mining; pattern classification; text analysis; Euclidean classifier; discriminative classification techniques; environmental DNA samples; genome identification; genomic fragments classification; inverted TF-IDF measure; text-mining approach; Bioinformatics; DNA; Data analysis; Euclidean distance; Frequency; Genomics; Performance evaluation; Phylogeny; Spatial databases; Testing;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Biomeidcine Workshops, 2008. BIBMW 2008. IEEE International Conference on
Conference_Location :
Philadelphia, PA
Print_ISBN :
978-1-4244-2890-8
Type :
conf
DOI :
10.1109/BIBMW.2008.4686216
Filename :
4686216
Link To Document :
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