Title :
Cancer classification by sparse representation using microarray gene expression data
Author_Institution :
Dept. of Electr. & Comput. Eng., California State Univ., Northridge, CA
Abstract :
In this paper, a new method is proposed for cancer diagnosis using gene expression data by casting the classification problem as finding sparse representations of test samples with respect to training samples. The sparse representation is efficiently computed by lscr1-regularized least square. Numerical experiment shows that the new approach can match the best performance achieved by support vector machines (SVM). Sparse representation approach also has no need of model selection.
Keywords :
cancer; least mean squares methods; medical computing; patient treatment; support vector machines; cancer classification; cancer diagnosis; microarray gene expression data; regularized least square; sparse representation; support vector machines; Cancer; Casting; Data engineering; Gene expression; Least squares methods; Neoplasms; Neural networks; Support vector machine classification; Support vector machines; Testing;
Conference_Titel :
Bioinformatics and Biomeidcine Workshops, 2008. BIBMW 2008. IEEE International Conference on
Conference_Location :
Philadelphia, PA
Print_ISBN :
978-1-4244-2890-8
DOI :
10.1109/BIBMW.2008.4686232