DocumentCode :
3535724
Title :
Impact of respiratory motion correction on the detection of small lesions in whole-body PET imaging: A simulation study
Author :
Marache-Francisco, S. ; Lamare, F. ; Fayad, H. ; Visvikis, D. ; Prost, R. ; Rouet, J.-M. ; Lartizien, C.
Author_Institution :
Medisys, Philips Healthcare, Suresnes, France
fYear :
2010
fDate :
Oct. 30 2010-Nov. 6 2010
Firstpage :
3531
Lastpage :
3533
Abstract :
Respiratory motion in Positron Emission Tomography leads to reduced image quality, influencing this way the quantitative accuracy of PET measurements, as shown in numerous studies. However, only few results have been published on its impact on lesion detection. This study intends to evaluate the impact of motion correction on the detection of small lesions (between 8 and 12 mm diameter) using a Computed-Aided Detection (CAD) system on FDG whole-body simulated PET images. We evaluate two types of motion correction techniques, both using motion fields derived from the reconstruction of gated PET images. The first technique consists in averaging the coregistered gated reconstructed PET images, while the second method integrates the motion fields during the iterative reconstruction process.
Keywords :
image motion analysis; image reconstruction; image registration; iterative methods; medical image processing; pneumodynamics; positron emission tomography; radioactive tracers; tumours; FDG whole-body simulated PET images; computed-aided detection system; coregistered gated reconstructed PET images; iterative method; lesions; positron emission tomography; respiratory motion correction; size 8 mm to 12 mm; Image reconstruction; Lesions; Liver; Lungs; Positron emission tomography; Solid modeling;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE
Conference_Location :
Knoxville, TN
ISSN :
1095-7863
Print_ISBN :
978-1-4244-9106-3
Type :
conf
DOI :
10.1109/NSSMIC.2010.5874465
Filename :
5874465
Link To Document :
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