Chronomes (rhythms, chaos, and age trends) of human heart rate variability in both genders

Author

Otsuka, K. ; Nishimu, Y. ; Kubo, Y. ; Cornélissen, G. ; Halberg, F.

Author_Institution

Dept. of Med., Daini Hosp., Tokyo, Japan

fYear

1997

fDate

7-10 Sep 1997

Firstpage

49

Lastpage

52

Abstract

Heart rate variability (HRV) may reflect autonomic nervous activity. From 24-hour Holter ECG records on 339 healthy subjects (222 M, 117 F), 3-92 years of age, time- and frequency-domain and chaotic measures (correlation dimension, CD, and complexity) of HRV were computed. Changes with age are not invariably linear: following a decrease until ~65 years, the rebound of RR50, SDmeans and the ~3.6 sec spectral power (“HF”(24h)) may represent particularly healthy long-lived subjects. Age-related changes are similar for males and females for SDANNs, SDmeans and the ~3.6 sec power, but differ for the ~10.5 sec/~3.6 sec power ratio which peaks ~46 years for males vs. ~34 years for females. Changes with age in CD are more pronounced by night than by day. The “sympathetic-parasympathetic” antiphase corresponds to physiologic considerations. Changes in HRV may contribute to the increased prevalence of cardiovascular disease with age

Keywords

chaos; electrocardiography; frequency-domain analysis; medical signal processing; time-domain analysis; 10.5 s; 24 h; 24-hour Holter ECG records; 3 to 92 y; 3.6 s; age trends; autonomic nervous activity; cardiovascular disease prevalence; chaotic measures; chronomes; gender; healthy subjects; human heart rate variability; parasympathetic; rhythms; sympathetic; Aging; Analysis of variance; Cardiovascular diseases; Chaos; Electrocardiography; Frequency measurement; Heart rate variability; Humans; Laboratories; Rhythm;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1997

Conference_Location

Lund

ISSN

0276-6547

Print_ISBN

0-7803-4445-6

Type

conf

DOI

10.1109/CIC.1997.647827

Filename

647827