Title :
Effects of iron oxide magnetic nanoparticles on osteoblast proliferation
Author :
Tran, N. ; Pareta, Rajesh ; Webster, Thomas
Author_Institution :
Dept. of Phys., Brown Univ., Providence, RI
Abstract :
Iron oxide nanoparticles are promising candidates for drug delivery systems to treat osteoporosis due to their biocompatibility and magnetic properties. Magnetite and maghemite nanoparticles were synthesized here using a co-precipitation method. The particles were characterized by transmission electron microscopy (TEM). Effects of CaP coating iron oxide magnetic nanoparticles on the proliferation of osteoblasts (OB) were determined after 1, 3 and 5 days of culture. The correlation of iron oxide nanoparticle concentration on OB density was also investigated.
Keywords :
biomagnetism; biomedical materials; bone; calcium compounds; coatings; drug delivery systems; iron compounds; nanobiotechnology; CaP; CaP coating; Fe2O3; Fe3O4; biocompatibility; coprecipitation method; drug delivery systems; iron oxide magnetic nanoparticles; maghemite nanoparticles; magnetite nanoparticles; osteoblast proliferation; osteoporosis; transmission electron microscopy; Amorphous magnetic materials; Bones; Calcium; Drug delivery; Iron; Magnetic properties; Magnetosphere; Nanoparticles; Osteoporosis; Saturation magnetization;
Conference_Titel :
Bioengineering Conference, 2009 IEEE 35th Annual Northeast
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-4362-8
Electronic_ISBN :
978-1-4244-4364-2
DOI :
10.1109/NEBC.2009.4967626
