DocumentCode :
3542784
Title :
A novel approach for alignments output storage problem facing clinical scenarios
Author :
Lu, Yiqi ; Chen, Yaoliang ; Yu, Fuli ; Xiao, Yanghua ; Xu, Danfeng
Author_Institution :
Sch. of Comput. Sci., Fudan Univ., Shanghai, China
fYear :
2011
fDate :
4-6 Dec. 2011
Firstpage :
174
Lastpage :
177
Abstract :
With ever-developing sequencing technologies, gaps between sequence mapping research work and commercial applications in clinical scenario are narrowing. However, the storage problem of alignment results is still a big challenge remained. From both storage and application perspectives, traditional approaches in alignments output files still leave much to be desired. In this paper, we try to explore on the above issues and propose a novel idea to tackle the alignments output storage problem under clinical scenarios. Experimental results show that when the coverage goes high, our method has an obvious advantage over BAM file. In addition, our method outperforms BAM file on the genomic position query on reads.
Keywords :
file organisation; genomics; medical administrative data processing; molecular orientation; BAM file; alignment output storage problem; alignments output files; clinical scenarios; commercial applications; genomic position query; sequence mapping research work; sequencing technologies; Bioinformatics; Conferences; Decision support systems; Genomics; Signal processing; USA Councils; TSP based recoding; binary file format; genome alignment;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Genomic Signal Processing and Statistics (GENSIPS), 2011 IEEE International Workshop on
Conference_Location :
San Antonio, TX
ISSN :
2150-3001
Print_ISBN :
978-1-4673-0491-7
Electronic_ISBN :
2150-3001
Type :
conf
DOI :
10.1109/GENSiPS.2011.6169473
Filename :
6169473
Link To Document :
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