Model-based optimal therapy for high-impact diseases

The current paper represents a continuation of the conference papers presented at the INES 2011 and 2012 conferences. A brief summary of the newest results in the field of physiological modeling and control are presented focusing on high public health impact diseases: diabetes, tumor and obesity. In the case of diabetes control, preliminary model-free results of the developed robust control framework is presented, while in the case of tumor control we have started to create a new tumor growth model based on clinical experiments. In the case of biostatistical investigation of obesity, new aspects of relationship between overweight/obesity and laboratory results was examined.