Title :
Beyond the microscope: embedded detectors for cell biology applications
Author :
Romani, Aldo ; Guerrieri, Roberto ; Tartagni, Marco ; Manaresi, Nicolò ; Medoro, Gianni
Author_Institution :
Adv. Res. Center on Electron. Syst., Bologna Univ., Italy
Abstract :
Embedding active sensing microelectronic substrates in microfluidic devices is a challenging feature in functional integration of complex bioanalytical protocols in lab-on-a-chip platforms. This paper reviews the design trade-offs of optical and impedance sensing techniques for cell biology imaging in view of their SNR limits. Results are discussed on the basis of experimental data of two prototypes.
Keywords :
biomedical optical imaging; biosensors; capacitive sensors; electric impedance imaging; microfluidics; microsensors; active sensing microelectronic substrates; bioanalytical protocols; capacitive sensors; cell biology imaging; detector SNR limits; embedded cell biology detectors; impedance sensing techniques; lab-on-a-chip; microfluidic devices; optical sensing techniques; Biological cells; Biomedical optical imaging; Detectors; Lab-on-a-chip; Microelectronics; Microfluidics; Microscopy; Optical design; Optical design techniques; Protocols;
Conference_Titel :
Circuits and Systems, 2005. ISCAS 2005. IEEE International Symposium on
Print_ISBN :
0-7803-8834-8
DOI :
10.1109/ISCAS.2005.1465236
