DocumentCode :
3546270
Title :
Femtomolar sensitivity DNA photonic crystal nanowire array ultrasonic mass sensor
Author :
Lu, Yuerui ; Peng, Songming ; Luo, Dan ; Lal, Amit
Author_Institution :
SonicMEMS Lab., Cornell Univ., Ithaca, NY, USA
fYear :
2012
fDate :
Jan. 29 2012-Feb. 2 2012
Firstpage :
88
Lastpage :
91
Abstract :
Femtomolar concentration DNA detection is important as this is the concentration needed for early-stage cancer and bacterial infection diagnosis application [1]. Here, we present the first-ever nanomechanical mass-sensing resonator with ordered vertical nanowire (NW) arrays on top of a Si/SiO2 bilayer thin membrane acting as a photonic crystal. The device has a very high surface area-to-volume ratio of 108 m-1, enabling DNA sensing of femtomolar concentration. Moreover, the nanowire array forms a photonic crystal that shows strong light trapping and absorption over broad-band optical wavelengths, enabling high-efficiency broad-band opto-thermo-mechanical remote device actuation and biosensing on chip. This method represents a mass-based platform technology that can sense molecules at low concentrations.
Keywords :
DNA; bio-optics; bioMEMS; biomedical ultrasonics; cancer; molecular biophysics; nanoelectromechanical devices; nanomedicine; nanowires; patient diagnosis; photonic crystals; photothermal effects; radiation pressure; DNA photonic crystal nanowire array; bacterial infection diagnosis; biosensing; cancer; femtomolar concentration DNA detection; femtomolar sensitivity; light absorption; light trapping; nanomechanical mass-sensing resonator; optothermomechanical remote device actuation; ultrasonic mass sensor; Arrays; Biomembranes; DNA; Optical resonators; Optical surface waves; Sensitivity; Silicon;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on
Conference_Location :
Paris
ISSN :
1084-6999
Print_ISBN :
978-1-4673-0324-8
Type :
conf
DOI :
10.1109/MEMSYS.2012.6170100
Filename :
6170100
Link To Document :
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