Title :
“Neural bypass” with hydrogel microfiber encapsulating neurons
Author :
Kato-Negishi, Midori ; Onoe, Hiroaki ; Takeuchi, Shoji
Author_Institution :
Inst. of Ind. Sci., Univ. of Tokyo, Tokyo, Japan
fDate :
Jan. 29 2012-Feb. 2 2012
Abstract :
This paper describes a “neural bypass” formed by hydrogel microfiber encapsulating neurons and glial cells. Using this bypass, we developed a technique to connect the separated neuronal regions without cell damage. We also demonstrated that a completely-transected cortical network was connected with the neural bypass. We believe that our neural bypass would be an extremely effective tool to connect damaged neuronal networks in the neurodegenerative diseases: cerebral infarction, stroke, brain trauma, Alzheimer´s disease.
Keywords :
brain; cellular biophysics; diseases; hydrogels; injuries; neurophysiology; Alzheimer disease; brain trauma; cerebral infarction; completely-transected cortical network; damaged neuronal network; glial cells; hydrogel microfiber; neural bypass; neurodegenerative diseases; neuronal region; stroke; Biological neural networks; Cells (biology); Fluorescence; Glass; Microscopy; Nerve fibers;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2012 IEEE 25th International Conference on
Conference_Location :
Paris
Print_ISBN :
978-1-4673-0324-8
DOI :
10.1109/MEMSYS.2012.6170349