• DocumentCode
    3549362
  • Title

    A high-throughput bioinformatics distributed computing platform

  • Author

    Keane, Thomas M. ; Page, Andrew J. ; McInerney, James O. ; Naughton, Thomas J.

  • Author_Institution
    Bioinformatics & Pharmacogenomics Lab., Nat. Univ. of Ireland, Maynooth, Ireland
  • fYear
    2005
  • fDate
    23-24 June 2005
  • Firstpage
    377
  • Lastpage
    382
  • Abstract
    In the past number of years the demand for high performance computing has greatly increased in the area of bioinformatics. The huge increase in size of many genomic databases has meant that many common tasks in bioinformatics are not possible to complete in a reasonable amount of time on a single processor. Recently distributed computing has emerged as an inexpensive alternative to dedicated parallel computing. We have developed a general-purpose distributed computing platform that is capable of using semi-idle computing resources to simulate a dedicated computing cluster. We have identified the suitability of a number of bioinformatics tasks to distributed computing. We briefly outline and evaluate two distributed bioinformatics programs, DSEARCH and DPRml, which have been developed for our system.
  • Keywords
    biology computing; database management systems; distributed programming; genetics; parallel machines; DPRml; DSEARCH; computing cluster; distributed bioinformatics program; distributed computing platform; genomic database; high-throughput bioinformatics; parallel computing; semiidle computing resource; single processor; Bioinformatics; Concurrent computing; Databases; Distributed computing; Genomics; Heuristic algorithms; High performance computing; Laboratories; Parallel processing; Phylogeny;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computer-Based Medical Systems, 2005. Proceedings. 18th IEEE Symposium on
  • ISSN
    1063-7125
  • Print_ISBN
    0-7695-2355-2
  • Type

    conf

  • DOI
    10.1109/CBMS.2005.11
  • Filename
    1467719