DocumentCode :
3560865
Title :
Apoptosis Experiments of Cultured Tumor Cells Treated With 200- 
-Sized Flexible Microplasma Jet
Author :
Kim, Jae Young ; Ballato, John ; Foy, Paul ; Hawkins, Thomas ; Wei, Yanzhang ; Li, Jinhua ; Kim, Sung-O
Author_Institution :
Holcombe Dept. of Electr. & Comput. Eng., Clemson Univ., Clemson, SC, USA
Volume :
39
Issue :
11
fYear :
2011
Firstpage :
2974
Lastpage :
2975
Abstract :
A flexible atmospheric pressure microplasma jet device utilizing a 200-μm hollow-core optical fiber was developed in order to trigger the apoptosis of cultured tumor cells and determine the feasibility of plasma endoscopy. As determined by in situ apoptosis assay, the TUNEL assay, this flexible microplasma jet induced cultured murine tumor cells to undergo apoptosis. In addition, the apoptosis was induced to a greater extent in B16F0 tumor cells than in CL.7 cells for the same plasma dose.
Keywords :
cancer; endoscopes; optical fibres; plasma applications; plasma devices; plasma jets; tumours; B16F0 tumor cells; TUNEL assay; apoptosis assay; cultured murine tumor cells; cultured tumor cell apoptosis; flexible microplasma jet device; hollow-core optical fiber; plasma dose; plasma endoscopy; pressure 1 atm; size 200 mum; Biomedical optical imaging; Cancer; Electron tubes; Malignant tumors; Medical treatment; Plasmas; Apoptosis experiment; flexible atmospheric pressure microplasma jet; plasma cancer therapy;
fLanguage :
English
Journal_Title :
Plasma Science, IEEE Transactions on
Publisher :
ieee
Conference_Location :
5/2/2011 12:00:00 AM
ISSN :
0093-3813
Type :
jour
DOI :
10.1109/TPS.2011.2134111
Filename :
5762368
Link To Document :
