• DocumentCode
    3561879
  • Title

    Scouting enzyme behavior

  • Author

    Matsumaru, Naoki ; Colombano, Silvano ; Zauner, Klaus-Peter

  • Author_Institution
    Dept. of Comput. Sci., Wayne State Univ., Detroit, MI, USA
  • Volume
    1
  • fYear
    2002
  • Firstpage
    19
  • Lastpage
    24
  • Abstract
    Experimental exploration of enzymatic response in a multidimensional context faces the challenge of an explosive number of possible milieu conditions. We address this problem with an evolutionary search strategy that scouts the physiochemical milieu space for unanticipated enzyme behavior and rewards the discovery of experimental conditions that yield surprises
  • Keywords
    biology computing; genetic algorithms; laboratory techniques; molecular biophysics; proteins; search problems; enzymatic response; enzyme; evolutionary experimentation; evolutionary search strategy; factor space; genotypes; milieu conditions; physiochemical milieu space; Application software; Biochemistry; Biological system modeling; Biological systems; Chemicals; Computer science; Explosives; Proteins; Resource management; Shape;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2002. CEC '02. Proceedings of the 2002 Congress on
  • Print_ISBN
    0-7803-7282-4
  • Type

    conf

  • DOI
    10.1109/CEC.2002.1006203
  • Filename
    1006203
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3561879