QRS complex detection in experimental orthogonal electrograms of isolated rabbit hearts

Automated analysis of HRV and/or QT intervals of isolated rabbit heart electrograms requires reliable detection of QRS complexes. We propose a detection method based on spatial velocity using differentiation of all lead signals, the squaring, the adding and the square root in orders. Teager-Kaiser energy operator was applied after filtering spatial velocity with a standard pass-band filter. The algorithm was tested on 263 orthogonal electrograms. Resulting values of both sensitivity and positive predictive value of detection increased 99.8%.