Title :
Development of scaffold for tissue engineering applications using imprinting
Author :
Vigneswaran, N. ; Samsuri, Fahmi ; Kalyani, K. Nithya
Author_Institution :
Fac. of Electr. & Electron. Eng., Univ. Malaysia Pahang, Pekan, Malaysia
Abstract :
In this article we report the development of scaffold mimicking the cell surface topography. Using Soft lithography, in which polymer (triglyme, ethylene glycol dimethacrylate, methacrylic acid and IRGAcure 2022) is applied over the cultured cell and cured instantly using UV source. IRGA cure 2022 is a photoinitiator, which helps in solidification of the polymer when exposed to UV light source. Triglyme helps to increase the viscosity of the polymer. This method can be applied to all adherent cells. This scaffold consists of cell surface topography features. The developed scaffold can pave way in tissue engineering for various applications and cell research investigations.
Keywords :
adhesion; biological tissues; biomechanics; biomedical materials; biomimetics; cellular biophysics; curing; light sources; soft lithography; surface topography; tissue engineering; viscosity; IRGAcure 2022; UV light source; adherent cells; cell surface topography features; cultured cell; ethylene glycol dimethacrylate; imprinting; methacrylic acid; photoinitiator; scaffold development; soft lithography; tissue engineering applications; triglyme; viscosity; Electronic countermeasures; Extracellular; Media; Polymers; Surface morphology; Tissue engineering; cell; extracellular matrix and tissue engineering; feature; morphology; scaffold;
Conference_Titel :
Science Engineering and Management Research (ICSEMR), 2014 International Conference on
Print_ISBN :
978-1-4799-7614-0
DOI :
10.1109/ICSEMR.2014.7043599