Title :
Design and fabrication of cell adhesion measuring device
Author :
Salehipour, Saeed ; Abolfathi, Nabiollah ; Hashemi, Ataallah
Author_Institution :
Dept. of Biomedicai Eng., Amirkabir Univ. of Technol., Tehran, Iran
Abstract :
Cell adhesion phenomena has an important role on different behavior of cell. Therefore qualitative and quantitative understanding of cell adhesion force is necessary. A low cost micro device has been developed that can demonstrate cell adhesion force against a specific mechanical stimuli. The device that we developed here allows the measuring cell adhesion. This device is made based on poly methyl methacrylate (PMMA). Finally, to test the system functions, we obtained viscoelastic parameters of cell by applying 10 micron displacement that had a good agreement with literature.
Keywords :
adhesion; bioMEMS; biological techniques; cellular biophysics; mechanical variables measurement; microfabrication; polymers; cell adhesion force; cell adhesion measuring device design; cell adhesion measuring device fabrication; cell adhesion phenomena; poly methyl methacrylate; specific mechanical stimuli; viscoelastic cell parameters; Adhesives; Biomedical engineering; Biomedical measurement; Force; Force measurement; Mathematical model; Springs; PMMA; cell adhesion force; in vitro; mechanical stimuli; microdevice; viscoelastic parameters;
Conference_Titel :
Biomedical Engineering (ICBME), 2014 21th Iranian Conference on
Print_ISBN :
978-1-4799-7417-7
DOI :
10.1109/ICBME.2014.7043943
