Title :
Volatolomics analysis using FTIR spectroscopy for breast cancer identification in vitro
Author :
Arshad, Ahmad Zulhilmi ; Munajat, Yusof ; Ibrahim, Raja Kamarulzaman Raja ; Hamdan, Salehhuddin ; Mahmood, Nasrul Humaimi
Author_Institution :
Fac. of Biosci. & Med. Eng., Univ. Teknol. Malaysia, Skudai, Malaysia
Abstract :
Volatolomic´s analysis is the technique to analysis the volatile organic compounds (VOCs) from the metabolites. VOCs are released by cancerous cells can be one of the bio-diagnostics techniques to diagnose the cancer. FTIR spectroscopy with White gas cell absorption techniques can analyse and detect the key species from VOCs released. Small amount of VOCs samples can be detected by vacuuming the White gas cell and a low concentration gas also can be detected by employing a long effective optical path-length gas chamber. In this preliminary study, methanol was detected from the VOCs released by breast cancer cells.
Keywords :
Fourier transform infrared spectroscopy; absorption; biochemistry; biomedical optical imaging; cancer; cellular biophysics; gases; mammography; organic compounds; FTIR spectroscopy; Fourier transform infrared spectroscopy; VOC released; biodiagnostics techniques; breast cancer cells; in vitro breast cancer identification; long effective optical path-length gas chamber; low concentration gas; volatile organic compounds; volatolomics analysis; white gas cell absorption techniques; Biomedical engineering; Breast cancer; Conferences; Medical diagnostic imaging; Methanol; Spectroscopy;
Conference_Titel :
Biomedical Engineering and Sciences (IECBES), 2014 IEEE Conference on
DOI :
10.1109/IECBES.2014.7047611