DocumentCode :
3566464
Title :
Spatiotemporal source localization with new reweighted method: a simulation study
Author :
Zhou, Yongxia ; Singh, Manbir
Author_Institution :
Dept. of Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
Volume :
4
fYear :
2003
Firstpage :
2776
Abstract :
Recently a smooth temporal activation model was introduced to include temporal a priori information for the spatiotemporal localization of EEG sources. The temporal and spatial smoothing constraints improved accuracy of reconstruction in noisy data, but the spatial resolution was relatively poor. We have investigated a novel approach where in addition to spatial and temporal smoothing constraints, we also apply a novel reweighting method to improve the spatiotemporal resolution. To evaluate our approach, we conducted a simulation study of the spatiotemporal reconstruction problem for synchronous and asynchronous sources in EEG. In one example, four separate regions where each region contained four synchronous sources that were asynchronous with respect to the other three regions were simulated, both in noise-free and noise-added situations. The results showed that all four regions are recoverable with our approach, at a higher spatiotemporal resolution than existing approaches.
Keywords :
electroencephalography; medical computing; neurophysiology; noise; spatiotemporal phenomena; EEG sources; asynchronous source; neuronal activities; noise-added situation; noise-free situation; noisy data reconstruction; reweighted method; simulation study; smooth temporal activation model; spatial resolution; spatial smoothing constraints; spatiotemporal reconstruction problem; spatiotemporal source localization; synchronous source; temporal a priori information; temporal smoothing constraints; Biomedical engineering; Biomedical measurements; Brain modeling; Electroencephalography; Image reconstruction; Laplace equations; Magnetic resonance imaging; Smoothing methods; Spatial resolution; Spatiotemporal phenomena;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium Conference Record, 2003 IEEE
ISSN :
1082-3654
Print_ISBN :
0-7803-8257-9
Type :
conf
DOI :
10.1109/NSSMIC.2003.1352462
Filename :
1352462
Link To Document :
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