DocumentCode
3573166
Title
Resonant slot antennas as transducers of DNA hybridization: a computational feasibility study
Author
Wichaidit, C. ; Peck, J.R. ; Zhang Lin ; Hamers, R.J. ; Hagness, S.C. ; van der Weide, D.W.
Author_Institution
Dept. of Electr. & Comput. Eng., Wisconsin Univ., Madison, WI, USA
Volume
1
fYear
2001
Firstpage
163
Abstract
We propose and simulate a resonant slot antenna for sensing DNA hybridization. Using simple geometric arguments for water displacement from a DNA-functionalized surface, we predict the changes in dielectric constants caused by hybridization. We conclude that these changes are significant enough to be detected in measurements of the resonant frequency and the surface currents of a slot antenna. These results motivate experimental work using these antennas as alternatives to current fluorescence probes.
Keywords
DNA; biosensors; permittivity; probes; slot antennas; surface chemistry; DNA hybridization; DNA-functionalized surface; computational feasibility study; dielectric constants; geometric arguments; resonant frequency; resonant slot antennas; surface currents; water displacement; Antenna measurements; Current measurement; DNA; Dielectric constant; Dielectric measurements; Frequency measurement; Resonance; Resonant frequency; Slot antennas; Transducers;
fLanguage
English
Publisher
ieee
Conference_Titel
Microwave Symposium Digest, 2001 IEEE MTT-S International
ISSN
0149-645X
Print_ISBN
0-7803-6538-0
Type
conf
DOI
10.1109/MWSYM.2001.966863
Filename
966863
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