A review of source separation and source localization approaches in peripheral nerves

Selectively monitoring the messages encoded in the electrical activity of peripheral nerves would enable us to improve the control of neuroprosthetic devices, which interface with the nervous system to help restore function after neurological injuries or amputations. By using multi-contact nerve cuff electrodes, which measure the electric potentials at several locations on the surface of the nerve, this task can be approached as an inverse problem of source localization. This review focuses on the attempts that have been made to apply source separation and source localization approaches to multi-contact nerve cuff recordings, and discusses future directions for these efforts.