Title :
Notice of Retraction
An approach for matabonomics data analysis applied on the urine of HB water extract administered rats
Author :
Qiyun Zhang ; Guoliang Xu ; Bingtao Li ; Xilan Tang ; Liping Huang ; Riyue Yu ; Hongning Liu
Author_Institution :
Key Lab. of Modern Preparation of TCM, Jiangxi Univ. of Traditional Chinese Med., Nanchang, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Data sets resulting from metabonomics or metabolic profiling experiments are becoming increasingly complex, which is hard to summarize and visualize without appropriate tools. The use of chemometric tools, such as orthogonal signal correction (OSC), principal component analysis (PCA), partial least squares to latent structure discriminant analysis (PLS-DA), make the data dimensionality reduction and interpretation much easier. Here we showed a system method based on PCA, PLS-DA for metabonomic data analysis; Furthermore, the loading plots of mass data, were used for the biomarkers discovery.
Keywords :
biology computing; data analysis; least squares approximations; principal component analysis; HB water extract urine; biomarkers discovery; chemometric tools; data dimensionality interpretation; data dimensionality reduction; latent structure discriminant analysis; matabonomics data analysis; metabolic profiling experiments; orthogonal signal correction; partial least squares; principal component analysis; Biological system modeling; Biomarkers; Matrix converters; Predictive models; Principal component analysis; Loading plot; Partial least squares to latent structure discriminant analysis (PLS-DA); Principal component analysis (PCA; Score plot;
Conference_Titel :
Computer Application and System Modeling (ICCASM), 2010 International Conference on
Print_ISBN :
978-1-4244-7235-2
DOI :
10.1109/ICCASM.2010.5619296