Title :
Harmonic holographic microscopy using nanoparticles as probes for three-dimensional cell imaging
Author :
Hsieh, Chia-Lung ; Grange, Rachel ; Pu, Ye ; Psaltis, Demetri
Author_Institution :
Opt. Lab., EPFL, Lausanne, Switzerland
Abstract :
We demonstrate the three-dimensional imaging capability of harmonic holographic microscopy by using the second harmonic generation from BaTiO3 nanoparticles as the signal. Three-dimensional distributions of the BaTiO3 nanoparticles in biological cells are recorded without scanning.
Keywords :
barium compounds; biological techniques; cellular biophysics; holography; nanoparticles; optical harmonic generation; optical microscopy; 3D cell imaging; BaTiO3; harmonic holographic microscopy; nanoparticle; second harmonic generation; Focusing; Holographic optical components; Holography; Hydrogen; Image reconstruction; Microscopy; Nanoparticles; Optical harmonic generation; Optical imaging; Probes; (090.1995) Digital holography; (160.4330) Nonlinear optical materials;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8