Title :
Study on Neural Regeneration Effect of Rat by Using Pulsed Functional Magnetic Stimulation
Author :
Naming Zhang ; Shuhong Wang ; Xinlin Chen ; Qindong Shi ; Jiangtao Li ; Jinyu Zhu ; Song Wang ; Bin Yang ; Youguang Guo ; Jianguo Zhu
Author_Institution :
State Key Lab. of Electr. Insulation & Power Equip., Xi´an Jiaotong Univ., Xi´an, China
Abstract :
Previous studies showed that the electromagnetic stimulation could effectively activate damaged neurons. However, electrical stimulation effects would be greatly decayed after penetrating into biological tissues. In this paper, based on the magnetic stimulation system, the principle of magnetic stimulation devices for sciatic nerves recovery is analyzed. The simulation based on Schwarz model and biological experiments are conducted. The selected 20 Sprague Dawley rats were divided into experimental group (Group A) and control group (Group B). Group A was given 30 min magnetic stimulation every day while none was given for Group B. The sciatic functional index and the maximum evoked potential of gastrocnemius muscle were obtained. The recovery rate of gastrocnemius muscle wet weight was obtained. The experimental results showed that Group A was superior to Group B, and the results were statistically significant. It is shown that the magnetic stimulation with appropriate frequency and amplitude is in favor of the recovery of injured sciatic nerve.
Keywords :
bioelectric potentials; muscle; neurophysiology; transcranial magnetic stimulation; Schwarz model; Sprague Dawley rats; activate damaged neurons; biological experiments; biological tissues; electrical stimulation effects; electromagnetic stimulation; gastrocnemius muscle; injured sciatic nerve; maximum evoked potential; neural regeneration effect; pulsed functional magnetic stimulation; sciatic functional index; sciatic nerve recovery; time 30 min; Coils; Electric fields; Electric potential; Magnetic fields; Magnetic stimulation; Nerve fibers; Rats; FEM; Finite Element Method (FEM); Magnetic stimulation; Nerve regeneration; Peripheral nerve; magnetic stimulation; nerve regeneration; peripheral nerve;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2015.2437997