A stochastic approach to solving inverse problems of biochemical networks

Advances in the development of models that can satisfactorily describe biochemical networks are extremely valuable for understanding life processes. In order to get full description of such networks, one has to solve the inverse problem, that is, estimate unknowns (rates and populations of various species) or choose models from a set of hypothesized models using experimental data. In this paper we discuss signal processing techniques for resolving the inverse problem of biochemical networks using the stochastic approach based on Bayesian theory. The proposed methods are tested in simple scenarios and the results are promising and suggest application of these methods to more complex networks.