Application of Bond Graph modeling on a fed-batch alcoholic fermentation bioprocess

In this paper the Bond Graph methodology is applied on a class of fed-batch biotechnological processes. First, Bond Graph model of a fed-batch prototype bioprocess is obtained by developing a set of rules, starting from the reactions schemes and taking into account the biochemical phenomena. Then, the rules used for the design of this model are applied on an alcoholic fermentation bioprocess that takes place also inside a fed-batch bio-reactor. This modeling procedure represents a valuable illustration of the power of Bond Graph methodology, and can be used as a base for the development of the models of bioprocesses with high level of complexity. Several simulations are conducted using 20sim modeling and simulation environment.