Title :
Clustering-based spot segmentation of cDNA microarray images
Author :
Volkan Uslan;İhsan Ömür Bucak
Author_Institution :
Computer Engineering Department, Fatih University, B.Cekmece, Istanbul, Turkey
Abstract :
Microarrays are utilized as that they provide useful information about thousands of gene expressions simultaneously. In this study segmentation step of microarray image processing has been implemented. Clustering-based methods, fuzzy c-means and k-means, have been applied for the segmentation step that separates the spots from the background. The experiments show that fuzzy c-means have segmented spots of the microarray image more accurately than the k-means.
Keywords :
"Pixel","Image segmentation","Clustering algorithms","Gene expression","Clustering methods","DNA"
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Print_ISBN :
978-1-4244-4123-5
Electronic_ISBN :
1558-4615
DOI :
10.1109/IEMBS.2010.5626430