• DocumentCode
    3644923
  • Title

    Fuzzy logic point of view applied to diseases caused by dynamic mutations

  • Author

    A. Savić;K. Jovanović;J. Mihailović;K. Radotić

  • Author_Institution
    Institute for multidisciplinary research, Belgrade, Serbia
  • fYear
    2011
  • Firstpage
    319
  • Lastpage
    321
  • Abstract
    For the first time, this paper tries to explain the origins of diseases caused by unstable DNA repeats, known as dynamic mutations. It is common to find fairly simplified correlation between the number of DNA repeats and severity of diseases. By examining the case studies, it is possible to see that simplified model does not reflect real condition of the patients, so we have proposed more complex model which involves gender, immunological condition, age of onset and analysis of family tree. Conclusions are related to known molecular biology phenomenon such as DNA methylation, histone binding and RNA secondary structure.
  • Keywords
    "Diseases","DNA","Mathematical model","Fuzzy logic","Artificial intelligence","Medical diagnostic imaging"
  • Publisher
    ieee
  • Conference_Titel
    Computational Intelligence and Informatics (CINTI), 2011 IEEE 12th International Symposium on
  • Print_ISBN
    978-1-4577-0044-6
  • Type

    conf

  • DOI
    10.1109/CINTI.2011.6108522
  • Filename
    6108522