DocumentCode
3644923
Title
Fuzzy logic point of view applied to diseases caused by dynamic mutations
Author
A. Savić;K. Jovanović;J. Mihailović;K. Radotić
Author_Institution
Institute for multidisciplinary research, Belgrade, Serbia
fYear
2011
Firstpage
319
Lastpage
321
Abstract
For the first time, this paper tries to explain the origins of diseases caused by unstable DNA repeats, known as dynamic mutations. It is common to find fairly simplified correlation between the number of DNA repeats and severity of diseases. By examining the case studies, it is possible to see that simplified model does not reflect real condition of the patients, so we have proposed more complex model which involves gender, immunological condition, age of onset and analysis of family tree. Conclusions are related to known molecular biology phenomenon such as DNA methylation, histone binding and RNA secondary structure.
Keywords
"Diseases","DNA","Mathematical model","Fuzzy logic","Artificial intelligence","Medical diagnostic imaging"
Publisher
ieee
Conference_Titel
Computational Intelligence and Informatics (CINTI), 2011 IEEE 12th International Symposium on
Print_ISBN
978-1-4577-0044-6
Type
conf
DOI
10.1109/CINTI.2011.6108522
Filename
6108522
Link To Document