DocumentCode :
3644923
Title :
Fuzzy logic point of view applied to diseases caused by dynamic mutations
Author :
A. Savić;K. Jovanović;J. Mihailović;K. Radotić
Author_Institution :
Institute for multidisciplinary research, Belgrade, Serbia
fYear :
2011
Firstpage :
319
Lastpage :
321
Abstract :
For the first time, this paper tries to explain the origins of diseases caused by unstable DNA repeats, known as dynamic mutations. It is common to find fairly simplified correlation between the number of DNA repeats and severity of diseases. By examining the case studies, it is possible to see that simplified model does not reflect real condition of the patients, so we have proposed more complex model which involves gender, immunological condition, age of onset and analysis of family tree. Conclusions are related to known molecular biology phenomenon such as DNA methylation, histone binding and RNA secondary structure.
Keywords :
"Diseases","DNA","Mathematical model","Fuzzy logic","Artificial intelligence","Medical diagnostic imaging"
Publisher :
ieee
Conference_Titel :
Computational Intelligence and Informatics (CINTI), 2011 IEEE 12th International Symposium on
Print_ISBN :
978-1-4577-0044-6
Type :
conf
DOI :
10.1109/CINTI.2011.6108522
Filename :
6108522
Link To Document :
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