Modification of drusen border detection algorithm based on flooding simulation

Drusen are white or yellow spots in eye fundus that consist of extracellular material. They are a sign of age-related macular degeneration (AMD) - the main cause of blindness in the developed countries and a third main cause of blindness in the whole world. Number and area of drusen are used to grade AMD. However, calculating them manually is time consuming. Thus various methods have been used to detect drusen automatically or semi-automatically. In this paper we propose an alternative method to find the borders of the drusen.