• DocumentCode
    3666452
  • Title

    Nanosecond pulsed electric field interactions with microglia and astrocytes

  • Author

    Salah Sommakia;Season Wyatt;Kevin Otto;Anand Vadlamani;Allen L. Garner

  • Author_Institution
    Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN
  • fYear
    2014
  • fDate
    6/1/2014 12:00:00 AM
  • Firstpage
    405
  • Lastpage
    407
  • Abstract
    Pulsed electrical fields (PEFs) that weaken the integrity of cellular membranes have been used for a variety of biomedical applications. Recent work suggests that nanosecond PEFs (nsPEFs) might be more beneficial than longer duration PEFs due to their slightly different mechanism of interaction with the cells. The nervous system presents an attractive, yet underutilized, biological target for nsPFE applications. In this paper we describe an in vitro primary mixed cortical cell system to test the effects of nsPFEs.
  • Keywords
    "Biomembranes","Nanobioscience","Electric fields","Cells (biology)","Electric potential","Neurons","Electrodes"
  • Publisher
    ieee
  • Conference_Titel
    Power Modulator and High Voltage Conference (IPMHVC), 2014 IEEE International
  • Print_ISBN
    978-1-4673-7323-4
  • Type

    conf

  • DOI
    10.1109/IPMHVC.2014.7287296
  • Filename
    7287296
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3666452