Complex optical method of cancer detection and visualization

A complex investigation of malignant tumors diagnosis was performed involving combined optical coherence tomography (OCT), Raman spectroscopy (RS) and autofluorescence (AF) analysis. Combined setup was used for common skin and lung malignant tumors analysis and for precise tissue morphology visualization. Fluorescence allows for scanning large tissue areas and detecting abnormal formations, while OCT helps to analyze tumor topology and invasion area. Adding RS analysis allows for precise determination of biomechanical composition of tumor and exact tumor type determination as a result. For skin pathologies analysis OCT may be useful in basal cell carcinomas diagnosis. RS allows for other malignant tumors determining both for skin and lung tissue (malignant melanoma for skin tissues, adenocarcinoma and squamous cell carcinoma for lung).