Title :
Regulation of nuclear morphology by actomyosin components and cell geometry
Author :
Nisha M. Ramdas;Qingsen Li;G.V. Shivashankar
Author_Institution :
National Centre for Biological Sciences, TIFR, Bangalore, India
Abstract :
Extracellular microenvironmental signals modulate the coupling between cytoskeleton to nuclear links to regulate gene expression profiles. However the influence of actomyosin assembly on the morphology of the nucleus is not well understood. In this paper, we quantitatively demonstrate the role of cell geometry and specific actomyosin molecular components in their control of nuclear morphology.
Keywords :
"Morphology","Computer architecture","Microprocessors","Geometry","Organizations","Shape","Surface morphology"
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE
Electronic_ISBN :
1558-4615
DOI :
10.1109/EMBC.2015.7318369