Title :
Photoacoustic immunoassay using plasmonic nanoparticles
Author :
Yunfei Zhao;Yin Huang;John F. McClelland;Xiangwei Zhao;Meng Lu
Author_Institution :
Department of Electrical and Computer Engineering, Iowa State University, Ames, 50011, USA
Abstract :
Immunoassay based on laser-induced photoacoustic (PA) effect is demonstrated for the detection of disease biomarkers with a significantly enhanced sensitivity. The PA immunoassay employs metal nanoparticles as photoacoustically detectable labels. Compared to the colorimetric method, the PA approach offers sensitivity improvements over 60-fold and 100-fold for the microtiter plate-based immunoassay and the lateral flow immunoassay, respectively.
Keywords :
"Immune system","Semiconductor device measurement"
Conference_Titel :
Photonics Conference (IPC), 2015
DOI :
10.1109/IPCon.2015.7323536
