LeVen - a parallel system for simulation of the heart left ventricle

We present the LeVen computational system for simulation of the electro-mechanical function of the left ventricle (LV) of mammalian heart on parallel computers. A macroscopic LV model incorporates state-of-the-art cellular models, e.g., Ekaterinburg-Oxford (EO) model [1] or ten Tusscher-Noble-Noble-Panfilov (TNNP) [2]. Ventricular mechanical activity on the organ level is described by means of the modified mass-spring system method, while the cellular mechanics is based on the myofilament activity. An open architecture of the LeVen system is proposed, which allows one to add and use new mechanical and electrophysiological models. The parallelization is implemented using the OpenMP technology. The performance of the LeVen system on multicore CPUs is evaluated. Parallel LeVen implementation provides a significant speedup, but the scalability is limited.