A multitechnique reconfigurable electrochemical biosensor for integration into mobile technologies

This paper describes the design and validation of a reconfigurable, multitechnique electrochemical biosensor intended for direct integration into smartphone and wearable technologies to realize a portable platform for Point-of-Care health monitoring. The reconfigurable potentiostat is able to perform various electrochemical techniques (amperometric, potentiometric, and impedance spectroscopy) and interfaces with several types of interchangeable electrochemical sensors all with a minimal number of components. A prototype of the reconfigurable potentiostat module was developed with discrete components, characterized, and compared against benchtop equipment. To show feasibility as well as flexibility of the platform, the device was used to run pH measurements and a glucose assay with comparable performance.