DocumentCode
3714587
Title
Parallel merging method to integrate different genome assemblies
Author
Kirill Romanenkov
Author_Institution
Faculty of Computational Mathematics and Cybernetics, Lomonosov Moscow State University, Russia
fYear
2015
Firstpage
1461
Lastpage
1464
Abstract
In this paper research in the field of application multiprocessor systems for genome assemblies reconciliation has been carried out. A large number of algorithmic approaches aimed to solve the task of de novo assembly from short reads, however the results of their work on the same raw data often differ essentially. A parallel algorithm for merging two or more assemblies without relying on a reference genome is presented. Due to the large data volume the computations in the distributed memory model on computational cluster are required. The proposed method integrates a combination of draft assemblies reducing resulting contigs fragmentation. Sequential version of the algorithm is implemented in C/C++ and is available at https://bitbucket.org/kromanenkov/gar.
Keywords
"Genomics","Bioinformatics","Assembly","Merging","Standards","Buildings","Databases"
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine (BIBM), 2015 IEEE International Conference on
Type
conf
DOI
10.1109/BIBM.2015.7359891
Filename
7359891
Link To Document