• DocumentCode
    3714587
  • Title

    Parallel merging method to integrate different genome assemblies

  • Author

    Kirill Romanenkov

  • Author_Institution
    Faculty of Computational Mathematics and Cybernetics, Lomonosov Moscow State University, Russia
  • fYear
    2015
  • Firstpage
    1461
  • Lastpage
    1464
  • Abstract
    In this paper research in the field of application multiprocessor systems for genome assemblies reconciliation has been carried out. A large number of algorithmic approaches aimed to solve the task of de novo assembly from short reads, however the results of their work on the same raw data often differ essentially. A parallel algorithm for merging two or more assemblies without relying on a reference genome is presented. Due to the large data volume the computations in the distributed memory model on computational cluster are required. The proposed method integrates a combination of draft assemblies reducing resulting contigs fragmentation. Sequential version of the algorithm is implemented in C/C++ and is available at https://bitbucket.org/kromanenkov/gar.
  • Keywords
    "Genomics","Bioinformatics","Assembly","Merging","Standards","Buildings","Databases"
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedicine (BIBM), 2015 IEEE International Conference on
  • Type

    conf

  • DOI
    10.1109/BIBM.2015.7359891
  • Filename
    7359891