Application of MEMS based capacitive sensor for continuous monitoring of glucose

We propose the application of MEMS capacitive pressure sensor for continuous glucose monitoring in diabetic patients. Two electrically charged parallel plates separated by a suitable dielectric medium, situated inside a micro-chamber isolated from the external environment by a felicitous semi-permeable membrane constitute the fundamental portion of the device. Determination of glucose concentration is achieved through the measurement of the pressure changes experienced by the capacitive pressure sensor, which is a result of change in viscosity of the test solution as an outcome of competitive binding of glucose. The test solution is an intermix of dextran (a polysaccharide) and concanavalin-A (con A). The capacitive pressure sensor is simulated using COMSOL Multiphysics.