DocumentCode
37239
Title
SuperQ: Computing Supernetworks from Quartets
Author
Grunewald, Stefan ; Spillner, Andrea ; Bastkowski, Sarah ; Bogershausen, Anja ; Moulton, Vincent
Author_Institution
CAS-MPG Partner Inst. for Comput. Biol., Shanghai, China
Volume
10
Issue
1
fYear
2013
fDate
Jan.-Feb. 2013
Firstpage
151
Lastpage
160
Abstract
Supertrees are a commonly used tool in phylogenetics to summarize collections of partial phylogenetic trees. As a generalization of supertrees, phylogenetic supernetworks allow, in addition, the visual representation of conflict between the trees that is not possible to observe with a single tree. Here, we introduce SuperQ, a new method for constructing such supernetworks (SuperQ is freely available at www.uea.ac.uk/computing/superq.). It works by first breaking the input trees into quartet trees, and then stitching these together to form a special kind of phylogenetic network, called a split network. This stitching process is performed using an adaptation of the QNet method for split network reconstruction employing a novel approach to use the branch lengths from the input trees to estimate the branch lengths in the resulting network. Compared with previous supernetwork methods, SuperQ has the advantage of producing a planar network. We compare the performance of SuperQ to the Z-closure and Q-imputation supernetwork methods, and also present an analysis of some published data sets as an illustration of its applicability.
Keywords
biology computing; genetics; trees (mathematics); QNet method; SuperQ; computing supernetwork; phylogenetics; quartet trees; split network; stitching process; supertrees; visual representation; Bioinformatics; Computational biology; Data visualization; Electronic mail; Phylogeny; Vegetation; Visualization; Supertree; consensus network; phylogenetic network; split network; supernetwork; Computational Biology; Databases, Genetic; Genes, Fungal; Genes, Plant; Models, Genetic; Phylogeny; Software;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2013.8
Filename
6425382
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