• DocumentCode
    3734803
  • Title

    Ultrasensitive nanosensor based on gold nanoparticles to detect vascular endothelial growth factor (VEGF)

  • Author

    JP Oliveira;RP Arruda;W Keijok;MA Cicilini;BV Nogueira;MCC Guimar?es;AR Prado;MRN Ribeiro;MJ Pontes

  • Author_Institution
    Departamento de Morfologia, Universidade Federal do Esp?rito Santo, Vitoria, Brazil
  • fYear
    2015
  • fDate
    7/1/2015 12:00:00 AM
  • Firstpage
    1049
  • Lastpage
    1053
  • Abstract
    We report on the use of new biosensor that enable a surface Plasmon resonance (SPR) sensor to detec VEGF in tissue extracts and cell lysates. This sensor consist of gold nanoparticles functionalized with antibodies anti-VEGF. To analyze the optical properties and their sensing ability was held optical absorption experiments in band plasmon resonance. We demonstrate that this approach makes it possible for the SPR biosensor to detect VEGF in tissues at low concentrations.
  • Keywords
    "Nanoparticles","Gold","Proteins","Plasmons","Biosensors","Biomedical optical imaging","Optical sensors"
  • Publisher
    ieee
  • Conference_Titel
    Nanotechnology (IEEE-NANO) , 2015 IEEE 15th International Conference on
  • Type

    conf

  • DOI
    10.1109/NANO.2015.7388801
  • Filename
    7388801
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3734803